{"product_id":"claudin-5-cldn5-antibody-western-blot-validated","title":"Claudin-5 (CLDN5) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eBring Claudin-5 into view to analyze changes across conditions. Claudin-5 is a structural regulator of intercellular boundaries and tissue architecture. Look for shifts in distribution that track with phenotype changes.\u003c\/p\u003e\n\u003cp\u003eTracking Claudin-5 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Endothelial model systems may track this target alongside barrier behavior and junction reorganization.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eFor size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-5 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Claudin-5 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eSelect the denaturing-format version to keep Claudin-5 interpretation aligned with your workflow goals.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102375776601,"sku":"00205-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102375809369,"sku":"00205-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102375842137,"sku":"00205-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102375874905,"sku":"00205-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102375907673,"sku":"00205-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102375940441,"sku":"00205-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn5-retina-1.jpg?v=1779283264","url":"https:\/\/absource.de\/products\/claudin-5-cldn5-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}