{"product_id":"claudin-8-cldn8-antibody-western-blot-validated","title":"Claudin-8 (CLDN8) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around Claudin-8 (CLDN8) and use this antibody to evaluate state-dependent differences. Claudin-8 is a membrane-associated component that helps organize cell-cell contacts and polarity. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eMonitoring Claudin-8 alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Predefine decision rules for excluding outliers so analysis remains transparent.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Claudin-8 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Claudin-8, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format option to keep Claudin-8 (CLDN8) analysis aligned with planned contrasts and endpoints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102359785817,"sku":"00208-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102359818585,"sku":"00208-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102359851353,"sku":"00208-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102359884121,"sku":"00208-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102359916889,"sku":"00208-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102359949657,"sku":"00208-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn8-kid-imagej-converted.jpg?v=1779283244","url":"https:\/\/absource.de\/products\/claudin-8-cldn8-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}