{"product_id":"clemastine-hs-592-fumarate-s1847","title":"Clemastine (HS-592)Fumarate","description":"\u003cp\u003e\u003cstrong\u003eClemastine (HS-592)Fumarate\u003c\/strong\u003e is an antagonist of MTOR and Histamine Receptors used in studies of PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking MTOR and Histamine Receptors, Clemastine (HS-592)Fumarate can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving MTOR and Histamine Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Clemastine (HS-592)Fumarate is appropriate when a defined chemical perturbant is needed to connect MTOR and Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805359710553,"sku":"S1847-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805359743321,"sku":"S1847-1G","price":461.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805359776089,"sku":"S1847-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/clemastine-fumarate-chemical-structure-S1847.gif?v=1776174120","url":"https:\/\/absource.de\/products\/clemastine-hs-592-fumarate-s1847","provider":"Absource Diagnostics","version":"1.0","type":"link"}