{"product_id":"clomipramine-hcl-s2541","title":"Clomipramine HCl","description":"\u003cp\u003e\u003cstrong\u003eClomipramine HCl\u003c\/strong\u003e is an inhibitor of Serotonin Transporter used in studies of Neurotransmission. In practice, this places the compound in experiments that measure synaptic signaling, receptor activity, and neuronal excitability in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Serotonin Transporter, Clomipramine HCl can be used to examine synaptic signaling, receptor activity, and neuronal excitability. The transporter annotation adds relevance to transport, uptake\/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Serotonin Transporter\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Neurotransmission\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Clomipramine HCl is appropriate when a defined chemical perturbant is needed to connect Serotonin Transporter with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805664518489,"sku":"S2541-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805664551257,"sku":"S2541-1G","price":658.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Clomipramine-hydrochloride-Anafranil-chemical-structure-S2541.gif?v=1776175233","url":"https:\/\/absource.de\/products\/clomipramine-hcl-s2541","provider":"Absource Diagnostics","version":"1.0","type":"link"}