{"product_id":"clozapine-n-oxide-cno-chemical-s6887","title":"Clozapine N-oxide (CNO chemical)","description":"\u003cp\u003e\u003cstrong\u003eClozapine N-oxide (CNO chemical)\u003c\/strong\u003e is an agonist of Dopamine Receptors and AChR used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating Dopamine Receptors and AChR, Clozapine N-oxide (CNO chemical) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Dopamine Receptors and AChR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Clozapine N-oxide (CNO chemical) is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors and AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809434673497,"sku":"S6887-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809434706265,"sku":"S6887-25MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809434739033,"sku":"S6887-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809434771801,"sku":"S6887-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809434804569,"sku":"S6887-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6887-clozapine-n-oxide-chemical-structure.gif?v=1776200639","url":"https:\/\/absource.de\/products\/clozapine-n-oxide-cno-chemical-s6887","provider":"Absource Diagnostics","version":"1.0","type":"link"}