{"product_id":"cm2-antibody-sc-f2910","title":"Muscarinic Acetylcholine Receptor 2\/CM2 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCM2 is a target of interest in many antibody-based workflows. The Muscarinic Acetylcholine Receptor 2 (M2 receptor) is a key member of the muscarinic acetylcholine receptor family, which belongs to the G protein-coupled receptor (GPCR) superfamily. It plays a central role in the parasympathetic regulation of the heart, particularly in controlling heart rate and myocardial contractility. Depending on the literature source, CM2 may also be discussed as Muscarinic Acetylcholine Receptor 2\/CM2 and Muscarinic Acetylcholine Receptor m2.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, membrane, and synapse, which can matter when signal is compared across treatments or changing cell states. Following CM2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCM2 is commonly interpreted in the context of neuroscience research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, membrane, and synapse, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, membrane, and synapse across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003edifferences between total target abundance and site-specific regulation when modified forms are compared\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CM2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CM2 reflect biology rather than handling. When interpreting CM2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CM2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577984950617,"sku":"F2910-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577984983385,"sku":"F2910-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577985016153,"sku":"F2910-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2910-wb.gif?v=1773600798","url":"https:\/\/absource.de\/products\/cm2-antibody-sc-f2910","provider":"Absource Diagnostics","version":"1.0","type":"link"}