{"product_id":"crb3-crumbs-3-antibody-ffpe-validated","title":"CRB3 (crumbs-3) Antibody - FFPE Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around CRB3 and use this antibody to characterize state-dependent differences. CRB3 is a membrane-associated component that helps organize cell-cell contacts and polarity. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol crumbs-3.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eWhen cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. Align controls to the expected direction of change to support confident interpretation.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting CRB3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eUse the fixed-section option to keep CRB3 analysis aligned with planned contrasts and endpoints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102276292953,"sku":"00240-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102276325721,"sku":"00240-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102276358489,"sku":"00240-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102276391257,"sku":"00240-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102276424025,"sku":"00240-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102276456793,"sku":"00240-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mouse-embryo-ffpe-section-e14-5-labeled-with-crb3-antibody-4096x2304-1_8660b0f5-3c05-4c9f-b230-616991ba0a6f.png?v=1779283111","url":"https:\/\/absource.de\/products\/crb3-crumbs-3-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}