{"product_id":"crt0044876-s7449","title":"CRT0044876","description":"\u003cp\u003e\u003cstrong\u003eCRT0044876\u003c\/strong\u003e is an inhibitor of DNA\/RNA Synthesis used in studies of DNA Damage Response. It is especially relevant in cancer and dna damage \/ repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA\/RNA Synthesis, CRT0044876 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA\/RNA Synthesis\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CRT0044876 is appropriate when a defined chemical perturbant is needed to connect DNA\/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 20 mg","offer_id":57809485332825,"sku":"S7449-20MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 50 mg","offer_id":57809485365593,"sku":"S7449-50MG","price":242.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 20 mg","offer_id":58478910538073,"sku":"C12696-20MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 50 mg","offer_id":58478910570841,"sku":"C12696-50MG","price":180.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/CRT0044876-chemical-structure-s7449.gif?v=1776201398","url":"https:\/\/absource.de\/products\/crt0044876-s7449","provider":"Absource Diagnostics","version":"1.0","type":"link"}