{"product_id":"ctnna1-antibody-sc-f1182","title":"CTNNA1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCTNNA1 (Catenin alpha 1) encodes α-catenin, a crucial cell adhesion protein that links cadherins to the actin cytoskeleton at adherens junctions, ensuring tissue integrity and signaling regulation. Structurally, it has an N-terminal domain that binds β-catenin or γ-catenin\/plakoglobin and a C-terminal region interacting with actin via vinculin or α-actinin. Depending on the literature source, CTNNA1 may also be discussed as alpha-Catenin and alpha E-catenin.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell junction, cell membrane, cytoplasm, and cytoskeleton, which can matter when signal is compared across treatments or changing cell states. Following CTNNA1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCTNNA1 is commonly interpreted in the context of cancer and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell junction, cell membrane, and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell junction, cell membrane, and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CTNNA1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CTNNA1 reflect biology rather than handling. When interpreting CTNNA1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CTNNA1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577641214297,"sku":"F1182-20UL","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577641247065,"sku":"F1182-100UL","price":319.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577641279833,"sku":"F1182-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1182-wb.gif?v=1773599395","url":"https:\/\/absource.de\/products\/ctnna1-antibody-sc-f1182","provider":"Absource Diagnostics","version":"1.0","type":"link"}