{"product_id":"curcurbitacin-iia-s5463","title":"Curcurbitacin IIA","description":"\u003cp\u003e\u003cstrong\u003eCurcurbitacin IIA\u003c\/strong\u003e is a natural product relevant to DNA Damage Response and Apoptosis and related signaling programs and associated biological responses. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects Curcurbitacin IIA to DNA Damage Response and Apoptosis and related signaling programs, supporting experiments that monitor checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions across biochemical, cellular, or phenotypic assay formats. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Apoptosis and related signaling programs\u003c\/li\u003e\n\u003cli\u003ePhenotypic screening and mechanism-deconvolution studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and dna damage \/ repair models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Curcurbitacin IIA is well suited to pathway-oriented studies that need a defined compound input for DNA Damage Response and Apoptosis and related signaling programs readouts in apoptosis, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 1 mg","offer_id":57809245602137,"sku":"S5463-1MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 mg","offer_id":58478745846105,"sku":"C11046-1MG","price":93.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/curcurbitacin-iia-chemical-structure-s5463.gif?v=1776198259","url":"https:\/\/absource.de\/products\/curcurbitacin-iia-s5463","provider":"Absource Diagnostics","version":"1.0","type":"link"}