{"product_id":"cxcl12-antibody-sc-f1523","title":"CXCL12\/SDF-1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCXCL12, also known as Stromal-cell-derived factor-1 (SDF-1), is a chemokine involved in numerous physiological processes, including embryonic development, organ homeostasis, leukocyte migration, stem cell homing, angiogenic activity and cancer metastasis. It exists in multiple splice variants, primarily SDF-1α and SDF-1β, SDF-1γ, expressed in the nervous system. Depending on the literature source, CXCL12 may also be discussed as CXCL12\/SDF-1 and SDF-1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes secreted, which can matter when signal is compared across treatments or changing cell states. Following CXCL12 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCXCL12 is commonly interpreted in the context of cancer, developmental biology, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans secreted, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within secreted relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CXCL12. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CXCL12 reflect biology rather than handling. When interpreting CXCL12, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CXCL12 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577769566553,"sku":"F1523-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577769599321,"sku":"F1523-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577769632089,"sku":"F1523-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1523-IHC1.jpg?v=1773599844","url":"https:\/\/absource.de\/products\/cxcl12-antibody-sc-f1523","provider":"Absource Diagnostics","version":"1.0","type":"link"}