{"product_id":"cyclin-b1-antibody-sc-f2522","title":"Cyclin B1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCyclin B1 is a regulatory protein essential for mitotic entry, acting as the regulatory subunit of the M-phase promoting factor (MPF) in vertebrates. It binds to and activates CDK1, forming a complex that triggers mitosis through phosphorylation of target proteins. Cyclin B1 accumulates during S and G2 phases, shuttles between the cytoplasm and nucleus, and becomes concentrated in the nucleus in late G2 before localizing to the centrosomes, mitotic spindle, and kinetochores during mitosis.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm, cytoskeleton, and nucleus, which can matter when signal is compared across treatments or changing cell states. Following Cyclin B1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCyclin B1 is commonly interpreted in the context of cell cycle research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm, cytoskeleton, and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm, cytoskeleton, and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in abundance, timing, or compartmental enrichment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for Cyclin B1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in Cyclin B1 reflect biology rather than handling. When interpreting Cyclin B1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep Cyclin B1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577957196121,"sku":"F2522-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577957228889,"sku":"F2522-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577957261657,"sku":"F2522-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2522-IF.png?v=1773600500","url":"https:\/\/absource.de\/products\/cyclin-b1-antibody-sc-f2522","provider":"Absource Diagnostics","version":"1.0","type":"link"}