{"product_id":"cyp17a1-antibody-sc-f2173","title":"Cytochrome P450 17A1\/CYP17A1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCytochrome P450 17A1\/CYP17A1 is a crucial enzyme in steroidogenesis, catalyzing both 17α-hydroxylation and C17,20-lyase reactions necessary for androgen biosynthesis. Structurally, it is a heme-containing monooxygenase, displaying a canonical cytochrome P450 fold with unique ligand-binding orientations. Expressed primarily in steroidogenic tissues such as the adrenal cortex, testes, and ovaries, it facilitates the conversion of pregnenolone and progesterone into precursors for glucocorticoids, androgens, and estrogens. Depending on the literature source, CYP17A1 may also be discussed as Cytochrome P450 17A1\/CYP17A1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes endoplasmic reticulum, membrane, and microsome, which can matter when signal is compared across treatments or changing cell states. Following CYP17A1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCYP17A1 is commonly interpreted in the context of endocrinology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans endoplasmic reticulum, membrane, and microsome, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between endoplasmic reticulum, membrane, and microsome across matched conditions\u003c\/li\u003e\n\u003cli\u003eresponses to hormone-dependent signaling or endocrine feedback context\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CYP17A1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CYP17A1 reflect biology rather than handling. When interpreting CYP17A1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CYP17A1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577880256857,"sku":"F2173-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577880289625,"sku":"F2173-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577880322393,"sku":"F2173-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2173-IF.png?v=1773600247","url":"https:\/\/absource.de\/products\/cyp17a1-antibody-sc-f2173","provider":"Absource Diagnostics","version":"1.0","type":"link"}