{"product_id":"d-ap5-e1246","title":"D-AP5","description":"\u003cp\u003e\u003cstrong\u003eD-AP5\u003c\/strong\u003e is an antagonist of NMDAR used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking NMDAR, D-AP5 can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NMDAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, D-AP5 is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804365693273,"sku":"E1246-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804365726041,"sku":"E1246-25MG","price":579.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1246-d-ap5-chemical-structure.png?v=1776166703","url":"https:\/\/absource.de\/products\/d-ap5-e1246","provider":"Absource Diagnostics","version":"1.0","type":"link"}