{"product_id":"diphenhydramine-e4827","title":"Diphenhydramine","description":"\u003cp\u003e\u003cstrong\u003eDiphenhydramine\u003c\/strong\u003e is an antagonist of Histamine Receptors used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in inflammation and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Histamine Receptors, Diphenhydramine can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Histamine Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Diphenhydramine is appropriate when a defined chemical perturbant is needed to connect Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"100 mg","offer_id":57804966527321,"sku":"E4827-100MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804966560089,"sku":"E4827-1G","price":776.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4827-Diphenhydramine-chemical-structure.png?v=1776170158","url":"https:\/\/absource.de\/products\/diphenhydramine-e4827","provider":"Absource Diagnostics","version":"1.0","type":"link"}