{"product_id":"dl-ap5-2-apv-e2979","title":"DL-AP5 (2-APV)","description":"\u003cp\u003e\u003cstrong\u003eDL-AP5 (2-APV)\u003c\/strong\u003e is an antagonist of NMDAR used in studies of Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling in neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking NMDAR, DL-AP5 (2-APV) can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NMDAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, DL-AP5 (2-APV) is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804651364697,"sku":"E2979-5MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804651397465,"sku":"E2979-25MG","price":372.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e2979-DL-AP5-2-APV-chemical-structure.png?v=1776168158","url":"https:\/\/absource.de\/products\/dl-ap5-2-apv-e2979","provider":"Absource Diagnostics","version":"1.0","type":"link"}