{"product_id":"dofetilide-s1658","title":"Dofetilide","description":"\u003cp\u003e\u003cstrong\u003eDofetilide\u003c\/strong\u003e is an inhibitor of Potassium Channels used in studies of ion-channel pharmacology. It is especially relevant in cardiovascular and neuroscience models, where defined compound exposure can be linked to ion conductance, membrane potential, and electrophysiological responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Potassium Channels, Dofetilide can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Potassium Channels\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cardiovascular and neuroscience models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Dofetilide is appropriate when a defined chemical perturbant is needed to connect Potassium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805331956057,"sku":"S1658-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805331988825,"sku":"S1658-200MG","price":658.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805332021593,"sku":"S1658-1G","price":1739.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Dofetilide-Tikosyn-chemical-structure-S1658.gif?v=1776173874","url":"https:\/\/absource.de\/products\/dofetilide-s1658","provider":"Absource Diagnostics","version":"1.0","type":"link"}