{"product_id":"dup-697-e1949","title":"DuP-697","description":"\u003cp\u003e\u003cstrong\u003eDuP-697\u003c\/strong\u003e is an inhibitor of COX and COX-2 used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting COX and COX-2, DuP-697 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving COX and COX-2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, DuP-697 is appropriate when a defined chemical perturbant is needed to connect COX and COX-2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804543656281,"sku":"E1949-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804543689049,"sku":"E1949-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804543721817,"sku":"E1949-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804543754585,"sku":"E1949-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1949-DuP-697-chemical-structure.png?v=1776167496","url":"https:\/\/absource.de\/products\/dup-697-e1949","provider":"Absource Diagnostics","version":"1.0","type":"link"}