{"product_id":"dynll1-pin-antibody-sc-f2116","title":"DYNLL1\/PIN Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eDYNLL1\/PIN is a target of interest in many antibody-based workflows. DYNLL1 (dynein light chain 1, also known as LC8-1 or PIN) is a small, highly conserved 10 kDa protein that regulates multiple neuronal functions. It is involved in the regulation of neuron proteins implicated in glaucomatous retinal ganglion cell (RGC) death, such as nitric oxide (NO) synthases, the pro-apoptotic protein Bim, and the dynein intermediate chain. Depending on the literature source, DYNLL1\/PIN may also be discussed as DYNLL1\/PIN.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm, cytoskeleton, microtubule organizing center, and centrosome, which can matter when signal is compared across treatments or changing cell states. Following DYNLL1\/PIN across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eDYNLL1\/PIN is commonly interpreted in the context of neuroscience and infectious disease research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm, cytoskeleton, and microtubule organizing center, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm, cytoskeleton, and microtubule organizing center across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003ehost-response changes during infection or pathogen-associated stimulation\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for DYNLL1\/PIN. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in DYNLL1\/PIN reflect biology rather than handling. When interpreting DYNLL1\/PIN, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep DYNLL1\/PIN trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577866592601,"sku":"F2116-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577866625369,"sku":"F2116-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577866658137,"sku":"F2116-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2116-IF.png?v=1773600191","url":"https:\/\/absource.de\/products\/dynll1-pin-antibody-sc-f2116","provider":"Absource Diagnostics","version":"1.0","type":"link"}