{"product_id":"elacridar-gf120918-s7772","title":"Elacridar (GF120918)","description":"\u003cp\u003e\u003cstrong\u003eElacridar (GF120918)\u003c\/strong\u003e is an inhibitor of P-gp used in studies of transporter biology. In practice, this places the compound in experiments that measure substrate uptake, efflux, and membrane-transport control in cancer and infectious disease models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting P-gp, Elacridar (GF120918) can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake\/efflux, and permeability assays, together with downstream-response mapping. In cancer and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving P-gp\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and infectious disease models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Elacridar (GF120918) is appropriate when a defined chemical perturbant is needed to connect P-gp with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 10 mg","offer_id":57809539694937,"sku":"S7772-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 50 mg","offer_id":57809539727705,"sku":"S7772-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 200 mg","offer_id":57809539760473,"sku":"S7772-200MG","price":783.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 g","offer_id":57809539793241,"sku":"S7772-1G","price":1248.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 ml (10mM\/DMSO)","offer_id":57809539826009,"sku":"S7772-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 10 mg","offer_id":58478975484249,"sku":"C12934-10MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 50 mg","offer_id":58478975517017,"sku":"C12934-50MG","price":271.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 200 mg","offer_id":58478975549785,"sku":"C12934-200MG","price":584.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 g","offer_id":58478975582553,"sku":"C12934-1G","price":932.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/elacridar-chemical-structure-s7772.gif?v=1776201832","url":"https:\/\/absource.de\/products\/elacridar-gf120918-s7772","provider":"Absource Diagnostics","version":"1.0","type":"link"}