{"product_id":"fk506-tacrolimus-s5003","title":"FK506 (Tacrolimus)","description":"\u003cp\u003e\u003cstrong\u003eFK506 (Tacrolimus)\u003c\/strong\u003e is an inhibitor linked to PI3K-Akt-mTOR Signaling and Autophagy and related pathway-oriented research. It is especially relevant in autophagy models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects FK506 (Tacrolimus) to PI3K-Akt-mTOR Signaling and Autophagy, supporting experiments that monitor growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation across biochemical, cellular, or phenotypic assay formats. This context is compatible with AKT\/mTOR readouts, pathway-response, and viability assays and autophagy-flux, lysosome, and cargo-clearance assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In autophagy models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in autophagy models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, FK506 (Tacrolimus) is well suited to pathway-oriented studies that need a defined compound input for PI3K-Akt-mTOR Signaling and Autophagy readouts in autophagy models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57809169809753,"sku":"S5003-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"500 mg","offer_id":57809169842521,"sku":"S5003-500MG","price":567.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809169875289,"sku":"S5003-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809169908057,"sku":"S5003-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/tacrolimus-fk506-chemical-structure-s5003.gif?v=1776197420","url":"https:\/\/absource.de\/products\/fk506-tacrolimus-s5003","provider":"Absource Diagnostics","version":"1.0","type":"link"}