{"product_id":"fkbp52-antibody-sc-f3799","title":"FKBP52 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eFKBP52 (FK506-binding protein 52 kDa) is a pivotal peptidylprolyl isomerase and cochaperone that plays a significant role in the regulation of steroid hormone receptors, including the androgen receptor (AR), glucocorticoid receptor (GR), and estrogen receptor (ER). Structurally, FKBP52 is characterized by a peptidylprolyl isomerase domain that facilitates protein folding and stabilization, as well as a tetratricopeptide repeat domain that mediates its interaction with heat shock protein 90 (Hsp90).\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell projection, cytoplasm, cytoskeleton, and microtubule, which can matter when signal is compared across treatments or changing cell states. Following FKBP52 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eFKBP52 is commonly interpreted in the context of endocrinology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell projection, cytoplasm, and cytoskeleton, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell projection, cytoplasm, and cytoskeleton across matched conditions\u003c\/li\u003e\n\u003cli\u003eresponses to hormone-dependent signaling or endocrine feedback context\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for FKBP52. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in FKBP52 reflect biology rather than handling. When interpreting FKBP52, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep FKBP52 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578047635801,"sku":"F3799-20UL","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578047668569,"sku":"F3799-100UL","price":289.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578047701337,"sku":"F3799-2X100UL","price":459.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3799-IF.png?v=1773601499","url":"https:\/\/absource.de\/products\/fkbp52-antibody-sc-f3799","provider":"Absource Diagnostics","version":"1.0","type":"link"}