{"product_id":"fli1-antibody-sc-f2418","title":"FLI1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eFLI1 (Friend leukemia integration 1) is a transcription factor belonging to the ETS family, characterized by its ETS DNA-binding domain. FLI1 is crucial for various biological processes, including cell proliferation, differentiation, migration, and apoptosis. It plays a key role in megakaryocyte differentiation, angiogenesis, and hematopoietic stem cell regulation.\u003c\/p\u003e\u003cp\u003eReported cellular context includes nucleus, which can matter when signal is compared across treatments or changing cell states. Following FLI1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eFLI1 is commonly interpreted in the context of cancer, immunology, and cardiovascular research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within nucleus relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003echanges linked to vascular, contractile, or hemodynamic cell-state cues\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for FLI1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in FLI1 reflect biology rather than handling. When interpreting FLI1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep FLI1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 20 µl","offer_id":57577938813273,"sku":"F2418-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 µl","offer_id":57577938846041,"sku":"F2418-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 2 × 100 µl","offer_id":57577938878809,"sku":"F2418-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 20 µl","offer_id":58477362217305,"sku":"C06196-20UL","price":116.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 µl","offer_id":58477362250073,"sku":"C06196-100UL","price":264.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2418-IHC1.jpg?v=1773600382","url":"https:\/\/absource.de\/products\/fli1-antibody-sc-f2418","provider":"Absource Diagnostics","version":"1.0","type":"link"}