{"product_id":"gambogenic-acid-s9031","title":"Gambogenic acid","description":"\u003cp\u003e\u003cstrong\u003eGambogenic acid\u003c\/strong\u003e is an inhibitor of FGFR used in studies of MAPK \/ ERK Signaling and Protein Degradation \/ Proteasome. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation in angiogenesis, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting FGFR, Gambogenic acid can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving FGFR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Protein Degradation \/ Proteasome\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Gambogenic acid is appropriate when a defined chemical perturbant is needed to connect FGFR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57809683284313,"sku":"S9031-1MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57809683317081,"sku":"S9031-10MG","price":658.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/gambogenic-acid-chemical-structure-s9031.gif?v=1776204876","url":"https:\/\/absource.de\/products\/gambogenic-acid-s9031","provider":"Absource Diagnostics","version":"1.0","type":"link"}