{"product_id":"geldanamycin-nsc-122750-s2713","title":"Geldanamycin (NSC 122750)","description":"\u003cp\u003e\u003cstrong\u003eGeldanamycin (NSC 122750)\u003c\/strong\u003e is an inhibitor of HSP90 used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer, endocrinology, and infectious disease models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HSP90, Geldanamycin (NSC 122750) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. This context is compatible with hormone-response, reporter, and receptor assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, endocrinology, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HSP90\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, endocrinology, and infectious disease models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Geldanamycin (NSC 122750) is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805704102233,"sku":"S2713-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805704135001,"sku":"S2713-50MG","price":658.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805704167769,"sku":"S2713-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805704200537,"sku":"S2713-1ML\/DMSO","price":373.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Geldanamycin-chemical-structure-s2713.gif?v=1776175563","url":"https:\/\/absource.de\/products\/geldanamycin-nsc-122750-s2713","provider":"Absource Diagnostics","version":"1.0","type":"link"}