{"product_id":"glembatumumab-vedotin","title":"Glembatumumab Vedotin","description":"\u003cp\u003e\u003cstrong\u003eGlembatumumab Vedotin\u003c\/strong\u003e is an antibody-drug conjugate (ADC) composed of a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to monomethyl auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker.\u003c\/p\u003e\u003ch2\u003eProduct overview\u003c\/h2\u003e\u003cp\u003eGlembatumumab vedotin is relevant to research on Breast cancer (TNBC) and advanced or metastatic melanoma. The product background identifies the antibody component, target antigen and payload or linker architecture where these details are supplied. This ADC context supports comparison of antigen recognition, payload conjugation and cellular uptake behavior in controlled assay systems, especially when researchers need to distinguish conjugated biologics from unconjugated antibodies or standalone small molecules.\u003c\/p\u003e\u003ch2\u003eLaboratory context\u003c\/h2\u003e\u003cp\u003eThe listed workflow context supports binding and uptake-oriented laboratory studies where a defined antibody component, cellular target and conjugated payload are relevant to assay planning, including cell-surface binding, cell-uptake and protein-binding experiments, within oncology research.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":58188062622041,"sku":"D4054-1MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"5 × 1 mg","offer_id":58188062654809,"sku":"D4054-5X1MG","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/a2-serial-chemical-structure_4a65590e-d409-40fb-b209-62b84a8d42c7.gif?v=1780390098","url":"https:\/\/absource.de\/products\/glembatumumab-vedotin","provider":"Absource Diagnostics","version":"1.0","type":"link"}