{"product_id":"gli2-antibody-ffpe-validated","title":"GLI2 Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eTo connect mechanism with measurement, this antibody lets you evaluate GLI2 in pathway-driven studies. GLI2 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eFollowing GLI2 across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting GLI2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eUse the fixed-section version to relate GLI2 behavior to upstream cues and downstream consequences.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101631484249,"sku":"50704-FFPE-50UL","price":530.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101631517017,"sku":"50704-FFPE-50UL+1UG","price":599.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101631549785,"sku":"50704-FFPE-50UL+10UG","price":649.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101631582553,"sku":"50704-FFPE-200UL","price":1130.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101631615321,"sku":"50704-FFPE-200UL+1UG","price":1199.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101631648089,"sku":"50704-FFPE-200UL+10UG","price":1249.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/gli2-e17-forebrain_1ffd2466-0c0d-41f1-bbad-d7000bcb6fe6.jpg?v=1779280788","url":"https:\/\/absource.de\/products\/gli2-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}