{"product_id":"gs-1427-e6559","title":"GS-1427","description":"\u003cp\u003e\u003cstrong\u003eGS-1427\u003c\/strong\u003e is an antagonist of Integrins used in studies of target-focused biology. It is especially relevant in angiogenesis and cancer models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Integrins, GS-1427 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with receptor-blockade and ligand-competition studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In angiogenesis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Integrins\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in angiogenesis and cancer models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, GS-1427 is appropriate when a defined chemical perturbant is needed to connect Integrins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57805028262233,"sku":"E6559-1MG","price":390.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E6559-chemical-structure.png?v=1776170905","url":"https:\/\/absource.de\/products\/gs-1427-e6559","provider":"Absource Diagnostics","version":"1.0","type":"link"}