{"product_id":"gsk2033-e1142","title":"GSK2033","description":"\u003cp\u003e\u003cstrong\u003eGSK2033\u003c\/strong\u003e is an antagonist of LXR used in studies of Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking LXR, GSK2033 can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving LXR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, GSK2033 is appropriate when a defined chemical perturbant is needed to connect LXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804334039385,"sku":"E1142-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804334072153,"sku":"E1142-25MG","price":372.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804334104921,"sku":"E1142-100MG","price":930.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804334137689,"sku":"E1142-1G","price":3921.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1142-gsk2033-chemical-structure.gif?v=1776166541","url":"https:\/\/absource.de\/products\/gsk2033-e1142","provider":"Absource Diagnostics","version":"1.0","type":"link"}