{"product_id":"gsk3326595-pemrametostat-epz015938-s8664","title":"GSK3326595 (Pemrametostat, EPZ015938)","description":"\u003cp\u003e\u003cstrong\u003eGSK3326595 (Pemrametostat, EPZ015938)\u003c\/strong\u003e is an inhibitor of PRMT used in studies of Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PRMT, GSK3326595 (Pemrametostat, EPZ015938) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PRMT\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, GSK3326595 (Pemrametostat, EPZ015938) is appropriate when a defined chemical perturbant is needed to connect PRMT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809632362841,"sku":"S8664-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809632395609,"sku":"S8664-25MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809632428377,"sku":"S8664-100MG","price":901.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809632461145,"sku":"S8664-1G","price":3901.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809632493913,"sku":"S8664-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/gsk3326595-chemical-structure-epz015938-S8664.gif?v=1776203972","url":"https:\/\/absource.de\/products\/gsk3326595-pemrametostat-epz015938-s8664","provider":"Absource Diagnostics","version":"1.0","type":"link"}