{"product_id":"guadecitabine-e8205","title":"Guadecitabine","description":"\u003cp\u003e\u003cstrong\u003eGuadecitabine\u003c\/strong\u003e is an inhibitor of DNA Methyltransferases and Transferases used in studies of Epigenetic Regulation and Metabolic Signaling. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in cancer, epigenetics, and immunology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA Methyltransferases and Transferases, Guadecitabine can be used to examine chromatin-state control, histone modification, and transcriptional regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, epigenetics, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA Methyltransferases and Transferases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Epigenetic Regulation and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Guadecitabine is appropriate when a defined chemical perturbant is needed to connect DNA Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, epigenetics, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818762346841,"sku":"E8205","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e8205-guadecitabine-chemical-structure-tube.png?v=1776276327","url":"https:\/\/absource.de\/products\/guadecitabine-e8205","provider":"Absource Diagnostics","version":"1.0","type":"link"}