{"product_id":"ha130-s0424","title":"HA130","description":"\u003cp\u003e\u003cstrong\u003eHA130\u003c\/strong\u003e is an inhibitor of PDE used in studies of enzyme regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to catalytic activity, substrate turnover, and enzymatic regulation in cardiovascular, metabolism, and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PDE, HA130 can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cardiovascular, metabolism, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PDE\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cardiovascular, metabolism, and neuroscience models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, HA130 is appropriate when a defined chemical perturbant is needed to connect PDE with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, metabolism, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805114868057,"sku":"S0424-5MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805114900825,"sku":"S0424-25MG","price":372.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0424-ha130-chemical-structure.png?v=1776172172","url":"https:\/\/absource.de\/products\/ha130-s0424","provider":"Absource Diagnostics","version":"1.0","type":"link"}