{"product_id":"halofuginone-s8144","title":"Halofuginone","description":"\u003cp\u003e\u003cstrong\u003eHalofuginone\u003c\/strong\u003e is an inhibitor of DNA\/RNA Synthesis and TGF-beta \/ Smad used in studies of TGF-beta \/ Smad Signaling and DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to Smad-mediated transcription, differentiation, and fibrotic signaling and checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and developmental biology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA\/RNA Synthesis and TGF-beta \/ Smad, Halofuginone can be used to examine Smad-mediated transcription, differentiation, and fibrotic signaling and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA\/RNA Synthesis and TGF-beta \/ Smad\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to TGF-beta \/ Smad Signaling and DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Halofuginone is appropriate when a defined chemical perturbant is needed to connect DNA\/RNA Synthesis and TGF-beta \/ Smad with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809582260569,"sku":"S8144-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809582293337,"sku":"S8144-25MG","price":468.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 mg","offer_id":57809582326105,"sku":"S8144-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 g","offer_id":57809582358873,"sku":"S8144-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58479000420697,"sku":"C13216-5MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58479000453465,"sku":"C13216-25MG","price":349.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 mg","offer_id":58479000486233,"sku":"C13216-100MG","price":712.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 g","offer_id":58479000519001,"sku":"C13216-1G","price":2928.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/halofuginone-chemical-structure-s8144.gif?v=1776202370","url":"https:\/\/absource.de\/products\/halofuginone-s8144","provider":"Absource Diagnostics","version":"1.0","type":"link"}