{"product_id":"hesperadin-s1529","title":"Hesperadin","description":"\u003cp\u003e\u003cstrong\u003eHesperadin\u003c\/strong\u003e is an inhibitor of AURKB used in studies of PI3K-Akt-mTOR Signaling and Cell Cycle Regulation. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint control, mitotic progression, and proliferation timing in cancer, cell cycle, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting AURKB, Hesperadin can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving AURKB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Cell Cycle Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Hesperadin is appropriate when a defined chemical perturbant is needed to connect AURKB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57805304201561,"sku":"S1529-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 10 mg","offer_id":57805304234329,"sku":"S1529-10MG","price":252.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 50 mg","offer_id":57805304267097,"sku":"S1529-50MG","price":696.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 g","offer_id":57805304299865,"sku":"S1529-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 ml (10mM\/DMSO)","offer_id":57805304332633,"sku":"S1529-1ML\/DMSO","price":343.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478454833497,"sku":"C07871-5MG","price":125.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 10 mg","offer_id":58478454866265,"sku":"C16371-10MG","price":188.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 50 mg","offer_id":58478454899033,"sku":"C07871-50MG","price":520.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 g","offer_id":58478454931801,"sku":"C07871-1G","price":2195.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Hesperadin-chemical-structure-S1529.gif?v=1776173683","url":"https:\/\/absource.de\/products\/hesperadin-s1529","provider":"Absource Diagnostics","version":"1.0","type":"link"}