{"product_id":"homoharringtonine-hht-s9015","title":"Homoharringtonine (HHT)","description":"\u003cp\u003e\u003cstrong\u003eHomoharringtonine (HHT)\u003c\/strong\u003e is an inhibitor of STAT and Autophagy used in studies of JAK-STAT Signaling and Autophagy. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting STAT and Autophagy, Homoharringtonine (HHT) can be used to examine cytokine-responsive transcriptional signaling and immune regulation and autophagic flux, lysosomal turnover, and stress adaptation. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving STAT and Autophagy\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Autophagy\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Homoharringtonine (HHT) is appropriate when a defined chemical perturbant is needed to connect STAT and Autophagy with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57809681645913,"sku":"S9015-1MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809681678681,"sku":"S9015-5MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809681711449,"sku":"S9015-100MG","price":1936.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809681744217,"sku":"S9015-1G","price":4904.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809681776985,"sku":"S9015-1ML\/DMSO","price":461.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/homoharringtonine-chemical-structure-s9015.gif?v=1776204865","url":"https:\/\/absource.de\/products\/homoharringtonine-hht-s9015","provider":"Absource Diagnostics","version":"1.0","type":"link"}