{"product_id":"icg-001-s2662","title":"ICG-001","description":"\u003cp\u003e\u003cstrong\u003eICG-001\u003c\/strong\u003e is an inhibitor of Wnt \/ beta-catenin used in studies of Wnt Signaling and Apoptosis. In practice, this places the compound in experiments that measure beta-catenin-dependent transcription and developmental signaling and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Wnt \/ beta-catenin, ICG-001 can be used to examine beta-catenin-dependent transcription and developmental signaling and caspase-associated cell-death signaling and survival decisions. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Wnt \/ beta-catenin\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Wnt Signaling and Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ICG-001 is appropriate when a defined chemical perturbant is needed to connect Wnt \/ beta-catenin with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805688865113,"sku":"S2662-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805688897881,"sku":"S2662-25MG","price":461.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805688930649,"sku":"S2662-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805688963417,"sku":"S2662-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805688996185,"sku":"S2662-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/icg001-chemical-structure-s2662.gif?v=1776175480","url":"https:\/\/absource.de\/products\/icg-001-s2662","provider":"Absource Diagnostics","version":"1.0","type":"link"}