{"product_id":"ilk1-antibody-sc-f0577","title":"ILK1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eILK1 is a target of interest in many antibody-based workflows. Integrin-linked kinases (ILKs) serve as mediators linking integrins and growth factors to downstream signaling pathways crucial for cell survival, cell cycle regulation, cell-cell adhesion, and cell motility. Functioning as a scaffold, ILK facilitates the connection between the extracellular matrix (ECM) and growth factor receptors with the actin cytoskeleton by interacting with integrin, PINCH (which connects ILK to receptor tyrosine kinases via Nck2), CH-ILKBP, and affixin. Depending on the literature source, ILK1 may also be discussed as ILK and Integrin linked ILK.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell junction, cell membrane, cell projection, and cytoplasm, which can matter when signal is compared across treatments or changing cell states. Following ILK1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eILK1 is commonly interpreted in the context of cancer and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell junction, cell membrane, and cell projection, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell junction, cell membrane, and cell projection across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for ILK1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in ILK1 reflect biology rather than handling. When interpreting ILK1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep ILK1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577472622937,"sku":"F0577-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577472655705,"sku":"F0577-100UL","price":379.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577472688473,"sku":"F0577-2X100UL","price":569.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0577-IHC1.jpg?v=1773598648","url":"https:\/\/absource.de\/products\/ilk1-antibody-sc-f0577","provider":"Absource Diagnostics","version":"1.0","type":"link"}