{"product_id":"incb086550-s9863","title":"INCB086550","description":"\u003cp\u003e\u003cstrong\u003eINCB086550\u003c\/strong\u003e is an inhibitor of PD-1 \/ PD-L1 used in studies of Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses in cancer, immunology, and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PD-1 \/ PD-L1, INCB086550 can be used to examine cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PD-1 \/ PD-L1\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, INCB086550 is appropriate when a defined chemical perturbant is needed to connect PD-1 \/ PD-L1 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809752621401,"sku":"S9863-5MG","price":470.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809752654169,"sku":"S9863-25MG","price":1402.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809752686937,"sku":"S9863-100MG","price":3528.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s9863-incb086550-chemical-structure.gif?v=1776205251","url":"https:\/\/absource.de\/products\/incb086550-s9863","provider":"Absource Diagnostics","version":"1.0","type":"link"}