{"product_id":"indole-2-carboxylic-acid-s6228","title":"Indole-2-carboxylic acid","description":"\u003cp\u003e\u003cstrong\u003eIndole-2-carboxylic acid\u003c\/strong\u003e is an inhibitor of Lipoxygenase used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant in inflammation and metabolism models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Lipoxygenase, Indole-2-carboxylic acid can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In inflammation and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Lipoxygenase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Indole-2-carboxylic acid is appropriate when a defined chemical perturbant is needed to connect Lipoxygenase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57809358324057,"sku":"S6228-25MG","price":95.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/indole-2-carboxylic-acid-chemical-structure-s6228.gif?v=1776199549","url":"https:\/\/absource.de\/products\/indole-2-carboxylic-acid-s6228","provider":"Absource Diagnostics","version":"1.0","type":"link"}