{"product_id":"itd-1-s6713","title":"ITD-1","description":"\u003cp\u003e\u003cstrong\u003eITD-1\u003c\/strong\u003e is an inhibitor of TGF-beta \/ Smad used in studies of TGF-beta \/ Smad Signaling. In practice, this places the compound in experiments that measure Smad-mediated transcription, differentiation, and fibrotic signaling in cancer, cell signaling, and developmental biology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting TGF-beta \/ Smad, ITD-1 can be used to examine Smad-mediated transcription, differentiation, and fibrotic signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TGF-beta \/ Smad\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to TGF-beta \/ Smad Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ITD-1 is appropriate when a defined chemical perturbant is needed to connect TGF-beta \/ Smad with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809414848857,"sku":"S6713-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809414881625,"sku":"S6713-25MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809414914393,"sku":"S6713-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/itd-1-chemical-structure-s6713.gif?v=1776200338","url":"https:\/\/absource.de\/products\/itd-1-s6713","provider":"Absource Diagnostics","version":"1.0","type":"link"}