{"product_id":"itf3756-e1469","title":"ITF3756","description":"\u003cp\u003e\u003cstrong\u003eITF3756\u003c\/strong\u003e is an inhibitor of HDAC used in studies of DNA Damage Response and Epigenetic Regulation. It is especially relevant in cancer, dna damage \/ repair, and epigenetics models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HDAC, ITF3756 can be used to examine checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage \/ repair, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HDAC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ITF3756 is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804399411545,"sku":"E1469-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804399444313,"sku":"E1469-25MG","price":579.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1469-ITF3756-chemical-structure.png?v=1776166913","url":"https:\/\/absource.de\/products\/itf3756-e1469","provider":"Absource Diagnostics","version":"1.0","type":"link"}