{"product_id":"jam-c-jam3-antibody-western-blot-validated","title":"JAM-C (JAM3) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to explore JAM-C (JAM3) in your model system. JAM-C is a structural regulator of intercellular boundaries and tissue architecture. Focus on trends across conditions rather than single-point snapshots.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol JAM3.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eThis denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing JAM-C measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting JAM-C, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eChoose the denaturing-format option when you want JAM-C (JAM3) results aligned to your sample format.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102261514585,"sku":"00253-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102261547353,"sku":"00253-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102261580121,"sku":"00253-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102261612889,"sku":"00253-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102261645657,"sku":"00253-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102261678425,"sku":"00253-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/jam-c-heart-e15.jpg?v=1779283051","url":"https:\/\/absource.de\/products\/jam-c-jam3-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}