{"product_id":"jnj-28583113-e5813","title":"JNJ-28583113","description":"\u003cp\u003e\u003cstrong\u003eJNJ-28583113\u003c\/strong\u003e is an antagonist of TRP Channels used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in cell signaling, neuroscience, and oxidative stress models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking TRP Channels, JNJ-28583113 can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cell signaling, neuroscience, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TRP Channels\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, JNJ-28583113 is appropriate when a defined chemical perturbant is needed to connect TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling, neuroscience, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804990382425,"sku":"E5813-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804990415193,"sku":"E5813-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804990447961,"sku":"E5813-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804990480729,"sku":"E5813-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E5813-JNJ-28583113-chemical-structure.png?v=1776170437","url":"https:\/\/absource.de\/products\/jnj-28583113-e5813","provider":"Absource Diagnostics","version":"1.0","type":"link"}