{"product_id":"jw55-s6745","title":"JW55","description":"\u003cp\u003e\u003cstrong\u003eJW55\u003c\/strong\u003e is an inhibitor of Wnt \/ beta-catenin used in studies of Wnt Signaling and DNA Damage Response. It is especially relevant in cancer, cell signaling, and developmental biology models, where defined compound exposure can be linked to beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Wnt \/ beta-catenin, JW55 can be used to examine beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Wnt \/ beta-catenin\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Wnt Signaling and DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, JW55 is appropriate when a defined chemical perturbant is needed to connect Wnt \/ beta-catenin with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809420812633,"sku":"S6745-5MG","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809420845401,"sku":"S6745-25MG","price":291.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/jw55-chemical-structure-s6745.gif?v=1776200390","url":"https:\/\/absource.de\/products\/jw55-s6745","provider":"Absource Diagnostics","version":"1.0","type":"link"}