{"product_id":"kb-r7943-mesylate-s4643","title":"KB-R7943 mesylate","description":"\u003cp\u003e\u003cstrong\u003eKB-R7943 mesylate\u003c\/strong\u003e is an inhibitor of NCX used in studies of MAPK \/ ERK Signaling and Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling in cardiovascular and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NCX, KB-R7943 mesylate can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and calcium flux, excitability, and secretion-linked signaling. The transporter annotation adds relevance to transport, uptake\/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NCX\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, KB-R7943 mesylate is appropriate when a defined chemical perturbant is needed to connect NCX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809098375513,"sku":"S4643-5MG","price":105.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s4643-kb-r7943-mesylate-chemical-structure.gif?v=1776196742","url":"https:\/\/absource.de\/products\/kb-r7943-mesylate-s4643","provider":"Absource Diagnostics","version":"1.0","type":"link"}