{"product_id":"kiaa0586-talpid3-human-c-terminus-antibody-ffpe-validated","title":"KIAA0586 (TALPID3) (Human) (C-Terminus) Antibody - FFPE Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eTo connect mechanism with measurement, this antibody lets you characterize KIAA0586 C-Terminus in pathway-driven studies. KIAA0586 C-Terminus is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol TALPID3.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eDisruption of intraflagellar transport or basal body function can produce distinct localization signatures. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eMany targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecell-cycle linked differences in localization\u003c\/li\u003e\n\u003cli\u003echanges in cilia incidence or apparent length in perturbation studies\u003c\/li\u003e\n\u003cli\u003eco-occurrence with intraflagellar transport markers\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for KIAA0586 C-Terminus so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing KIAA0586 C-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section option supports mechanistic reading of KIAA0586 C-Terminus when interactions and context are the focus.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101336441177,"sku":"90711C-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101336473945,"sku":"90711C-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101336506713,"sku":"90711C-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101336539481,"sku":"90711C-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101336572249,"sku":"90711C-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101336605017,"sku":"90711C-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/kiaa0586-structure_466580d7-47fb-467e-aab8-3d569a06c366.jpg?v=1779279223","url":"https:\/\/absource.de\/products\/kiaa0586-talpid3-human-c-terminus-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}