{"product_id":"klotho-kl-antibody-ffpe-validated","title":"Klotho (KL) Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody is suited for researchers who want to investigate Klotho and relate it to cell-state biology. Klotho is a signaling node often evaluated by abundance, localization, and modification-dependent states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eMonitoring Klotho alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eIn practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Klotho so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Klotho patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eAs you refine hypotheses around Klotho, the fixed-section format helps keep conclusions tied to preparation context.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101521449305,"sku":"52100-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101521482073,"sku":"52100-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101521514841,"sku":"52100-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101521547609,"sku":"52100-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101521580377,"sku":"52100-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101521613145,"sku":"52100-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/klotho-kid-pfa_49ab59f1-19f8-47f6-b933-c6a0d6f57ddb.jpg?v=1779280169","url":"https:\/\/absource.de\/products\/klotho-kl-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}