{"product_id":"lithocholic-acid-s4003","title":"Lithocholic acid","description":"\u003cp\u003e\u003cstrong\u003eLithocholic acid\u003c\/strong\u003e is an agonist of FXR and Vitamin D Receptor and related targets used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating FXR and Vitamin D Receptor and related targets, Lithocholic acid can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving FXR and Vitamin D Receptor and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Lithocholic acid is appropriate when a defined chemical perturbant is needed to connect FXR and Vitamin D Receptor and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57808983621977,"sku":"S4003-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57808983654745,"sku":"S4003-1G","price":658.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57808983687513,"sku":"S4003-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"url":"https:\/\/absource.de\/products\/lithocholic-acid-s4003","provider":"Absource Diagnostics","version":"1.0","type":"link"}