{"product_id":"lrp2-megalin-antibody-western-blot-validated","title":"LRP2 (megalin) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody enables you to evaluate LRP2 with a direct, biology-first readout. LRP2 is a filament-associated component linked to spatial organization within cells. Focus on trends across conditions rather than single-point snapshots.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol megalin.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eDrug perturbations that affect polymerization or contractility can shift distribution and complex formation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Kidney-focused model systems may monitor this target when evaluating transport, barrier features, or compartment identity.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003edifferences across cell density or substrate stiffness\u003c\/li\u003e\n\u003cli\u003estress-fiber versus cortical distribution patterns\u003c\/li\u003e\n\u003cli\u003eremodeling after perturbation of polymerization or contractility\u003c\/li\u003e\n\u003cli\u003eassociation with junctional complexes or focal adhesions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing LRP2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eWith a clear focus on LRP2, this denaturing-format option fits streamlined studies and fast iteration.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101697872217,"sku":"31012-WB-50UL","price":530.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101697904985,"sku":"31012-WB-50UL+1UG","price":599.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101697937753,"sku":"31012-WB-50UL+10UG","price":649.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101697970521,"sku":"31012-WB-200UL","price":1130.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101698003289,"sku":"31012-WB-200UL+1UG","price":1199.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101698036057,"sku":"31012-WB-200UL+10UG","price":1249.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mgln-kid-low-mag-pfa.jpg?v=1779281105","url":"https:\/\/absource.de\/products\/lrp2-megalin-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}