{"product_id":"mcam-cd146-or-muc18-antibody-ffpe-validated","title":"MCAM (CD146 or MUC18) Antibody - FFPE Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eWhen you need to investigate MCAM (CD146) with attention to cellular organization, this antibody provides a focused option. MCAM is a lineage-associated marker that supports stratification of immune populations in model systems. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol CD146.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eExperimental perturbations such as cytokine exposure can reshape marker abundance and localization patterns. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Stem or progenitor models may incorporate this target when mapping state transitions and lineage drift.\u003c\/p\u003e\n\u003cp\u003eMany targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eactivation-dependent changes across stimulation conditions\u003c\/li\u003e\n\u003cli\u003epanel-based interpretation with additional lineage markers\u003c\/li\u003e\n\u003cli\u003eassessment of surface versus internalized pools\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eIn sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for MCAM so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section version supports deeper biological narratives around MCAM (CD146) without overcomplicating setup.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102153544025,"sku":"01005-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102153576793,"sku":"01005-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102153609561,"sku":"01005-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102153642329,"sku":"01005-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102153675097,"sku":"01005-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102153707865,"sku":"01005-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mcam-lung-e14-sharped_9bf56191-0db7-4051-b661-d5221cbd8e69.jpg?v=1779282864","url":"https:\/\/absource.de\/products\/mcam-cd146-or-muc18-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}